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How Funders Recognise a True Entrepreneur: The Good, the Bad and the Ugly
Explore how funders assess entrepreneurs, from commitment and cash planning to confidentiality, leadership, investor bias and common misconceptions

Stephanus Marais
Oct 67 min read


Too Old to Start a Biotech Business: The Bigger Question Is What It Takes to Build One
I began my entrepreneurial journey later in life, confident that my experience had prepared me well. I had written bankable business plans for start-up ventures, raised millions of rand in funding and helped establish several spin-out companies from the organisation where I worked. I understood both science and business, and thought I knew what it took to build a company. Starting six companies of my own over the following two years showed me how much I still had to learn. It

Stephanus Marais
Sep 297 min read


Crafting a Bankable Business Plan for Biotechnology and Deep-Tech Start-Ups
What makes a business plan bankable? Maravion explains why biotech and deep-tech start-ups need strong financial models, valuations and commercialisation strategies.

Stephanus Marais
Sep 108 min read


Exploring the World of Biopharmaceutical Innovations
The landscape of healthcare and medicine is evolving rapidly, driven by breakthroughs in science and technology. Among these advancements, biopharmaceutical innovations stand out as a transformative force. These innovations are reshaping how we approach treatment, drug development, and patient care. As we explore this dynamic field, we will uncover the key concepts, technologies, and opportunities that define the world of biopharmaceuticals. The Rise of Biopharmaceutical Inno

Stephanus Marais
Sep 75 min read


Commercialising Indigenous Knowledge Systems: A South African Approach
Indigenous Knowledge Systems (IKS) hold immense value in South Africa’s cultural and economic landscape. These systems encompass traditional wisdom, practices, and innovations that have been passed down through generations. As we explore the commercialisation of indigenous knowledge, it is essential to understand how this process can be structured to benefit local communities, startups, and industries alike. Our focus is on practical strategies that enable the transformation

Stephanus Marais
Sep 13 min read


Succeeding with Biotech Startup Strategies in South Africa
A critical element is securing funding. South African biotech startups should explore diverse funding avenues, including government grants, venture capital, and international partnerships. Understanding the funding landscape and tailoring proposals to meet investor expectations is vital

Stephanus Marais
Sep 13 min read


Building a Stronger Cosmetics Sector in South Africa
Maravion supported five South African SMMEs to develop 20 market-ready cosmetic products using UWC's proprietary Cotisyl technology, combining product formulation, scientific testing, branding, IP and manufacturing support

Stephanus Marais
Aug 306 min read


Skin in the Game: What It Really Takes to Build a Deep-Tech Business
Skin in the Game: What It Really Takes to Build a Deep-Tech Business”, I would optimise around deep-tech entrepreneurship, biotech entrepreneurship, start-up funding and founder characteristics.
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Stephanus Marais
Aug 177 min read


Deep Tech Does Not Face One Valley of Death. It Faces Three
Deep-tech startups face more than one Valley of Death. Maravion explores three critical funding gaps spanning R&D and commercialisation, market access, and growth and expansion, and why South Africa's innovation ecosystem needs to address all three

Stephanus Marais
Aug 128 min read


Continuous Flow Chemistry for API Manufacturing: Powerful Technology, but Not a Universal Solution
Explore when continuous flow chemistry creates value in active pharmaceutical ingredient manufacturing, and when solvent recovery, solubility and process economics favour batch or hybrid manufacturing.

Stephanus Marais
Aug 77 min read


The Biopharmaceutical Industry Landscape: Why Industry Mapping is Critical for Investment, Manufacturing and Commercialisation
The global biopharmaceutical industry is transforming healthcare at an unprecedented pace. From monoclonal antibodies and biosimilars to mRNA vaccines, gene therapy and personalised medicine, biologics are changing how diseases are prevented, diagnosed and treated. As governments, investors, manufacturers and research organisations seek to strengthen their life sciences sectors, one question has become increasingly important

Stephanus Marais
Aug 45 min read


Pharmaceutical Industry Landscape Mapping: Building Competitive Pharmaceutical Manufacturing for the Future
Pharmaceutical industry mapping is the systematic assessment of an entire pharmaceutical ecosystem. Rather than focusing on a single product or manufacturing facility, it evaluates every component required to establish a sustainable and competitive pharmaceutical industry.

Stephanus Marais
Jul 305 min read


Effective Indigenous Product Strategies for IKS Product Commercialisation
Bringing Indigenous Knowledge Systems (IKS) products to market requires a strategic approach that respects cultural heritage while meeting modern commercial demands. As we navigate the complexities of product development and market entry, it is essential to adopt effective indigenous product strategies that align with both innovation and tradition. This post explores practical methods to successfully commercialize IKS products, focusing on deep-tech startups, SMMEs, universit

Stephanus Marais
Jul 284 min read


The Roadmap to Commercialising Indigenous Knowledge Systems: Herbal and Traditional Medicines
Why Herbal and Traditional Medicines Matter in Africa Africa possesses one of the world’s richest repositories of Indigenous Knowledge Systems (IKS). This wealth includes centuries of accumulated knowledge related to medicinal plants, traditional healing practices, and natural therapies. Across South Africa, Indigenous Knowledge continues to provide valuable opportunities for developing innovative herbal medicines. These medicines address local healthcare needs while meeting

Stephanus Marais
Jul 214 min read


From Prostate Health to Hair Growth: what Elephantorrhiza Elephantina Teaches us about Indigenous Knowledge Commercialisation
Africa’s Indigenous Knowledge Systems (IKS) continue to reveal valuable opportunities for biotechnology, natural product innovation, and phytopharmaceutical development. One compelling example is Elephantorrhiza elephantina, a medicinal plant historically used across southern Africa to treat bladder conditions, urinary tract infections, infertility, wound healing, and other ailments. For generations, traditional healers recognised the therapeutic value of this plant, particul

Stephanus Marais
Jul 172 min read


Exploring Maravion Services: Driving Deep-Tech Innovation Forward
In the rapidly evolving landscape of technology and innovation, the role of strategic partners in industrialising deep-tech inventions cannot be overstated. Maravion has emerged as a pivotal player in South Africa and the broader African continenet, offering comprehensive support to startups, universities, incubators, and innovation hubs. Our focus is on enabling these entities to commercialise their inventions effectively and secure the necessary funding to scale their impac

Stephanus Marais
Jul 143 min read


The Roadmap to Commercialising Indigenous Knowledge Systems: Where Does Your Innovation Journey Begin?
At Maravion we believe that successful Indigenous Knowledge commercialisation begins long before a product reaches the market. Through commercialisation strategy, market assessment, techno-economic analysis, regulatory planning, intellectual property valuation, business planning, and investor readiness support, we help innovators identify the pathway most likely to achieve both commercial success and meaningful social impact.

Stephanus Marais
Jul 103 min read


Exploring African Innovation Hubs: Driving Deep-Tech Growth Across the Continent
Africa is rapidly emerging as a fertile ground for innovation, particularly in the deep-tech sector. Across the continent, a network of innovation hubs, incubators, and universities is fostering an environment where startups and small to medium enterprises (SMMEs) can thrive. These hubs are not only nurturing ideas but also helping to commercialize inventions and secure funding, which is essential for industrializing deep-tech innovations. This deep tech commercialisation blo

Stephanus Marais
Jul 34 min read


Beyond the Patent: A Practical Approach to Intellectual Property Valuation
Whether you are commercialising university research, raising investment for a biotechnology start-up, licensing a new technology, or evaluating an innovation portfolio, understanding the value of your intellectual property (IP) is essential. Intellectual property often represents the most valuable asset in a technology-based business. However, determining its true value requires far more than estimating development costs or assigning a value to a patent. Effective IP valuatio

Stephanus Marais
Jun 304 min read


Company C: A Journey of Reinvention in Biotechnology
From Commercialisation to Independent Biotech Company C began with a deeply entrepreneurial decision: to move from supporting the commercialisation of other technologies to building an independent biotech business from the ground up. Founded around enzyme and product development, the company initially entered the market with a focus on speciality enzymes and research reagents. However, like many science-based ventures, early assumptions about market attractiveness quickly enc

Stephanus Marais
Jun 232 min read
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